Mechanical and Civil Engineering Seminar
Mechanical and Civil Engineering Seminar Series
Title: Digital twin modeling of blood flow
Abstract:
Combining medical imaging and other clinical data with mathematical modeling has become an important paradigm in digital twin modeling of cardiovascular dynamics. Such modeling often entails two major steps. The first is development of a patient-specific computer model, and the second is simulating the physiology. This talk will discuss recent efforts to automate and speed up this, previously time-consuming, process using machine learning and reduced-order simulation, and concomitantly, the open-source project, SimVascular, which provides a platform for image-based simulation analysis.
Additionally, the presentation outlines the development of a probabilistic wildfire risk assessment framework, inspired by decades of progress in earthquake risk engineering. This framework accounts for uncertainties across different systems to quantify wildfire risk as the probability of loss. Finally, we explore key technical challenges in wildfire monitoring, simulation, and data assimilation and present a forward-looking vision for wildfire engineering research. The objective is to engage the engineering community in addressing this critical and evolving challenge through innovative contributions.
Bio: Shawn Shadden is a Professor of Mechanical Engineering at the University of California, Berkeley and a core member of the UCSF-UC Berkeley Graduate Program in Bioengineering. His research focuses on the computational modeling of cardiovascular biomechanics and the advancement of theoretical and numerical methods to quantify complex fluid flow. He is recipient of the NSF CAREER Award, Bakar Faculty Fellow Award, Hellman Faculty Fellow Award, and American Heart Association's Established Investigator Award. His lab helps develop the SimVascular software platform, widely used in the field of cardiovascular modeling.
NOTE: At this time, in-person Mechanical and Civil Engineering Lectures are open to all Caltech students/staff/faculty/visitors.